Kaitlyn, but with Brayden, they were a must. I gave them to him after every meal for quite some time. If your baby is fussy, keep the possibility of gas in mind. If you think it is gas, give him drops. They made a huge difference on Brayden's disposition.
2013 edit: We used these with McKenna and Brinley also. They were a must for Brinley like they were for Brayden. These are the kind we used:
Equate - Infants' Gas Relief Drops, Simethicone 20 mg, 1 fl oz
We also used gripe water with McKenna and Brinley. Gripe water was not a regular thing for us, but it was great for quickly getting rid of hiccups. It also helped with Brinley when she would spit up a lot. Here is our favorite kind:
Mommy's Bliss Gripe Water, Liquid, 4-ounce bottle